OECD 112

Dissociation constants in water

The dissociation is the reversible splitting into two or more chemical species which may be ionic.

Titration methods are classically performed at Phytosafe: a known amount of substance is titrated with standard acid or base, as appropriate.

The study aimed at the determination of the pKa values which predict whether the substance will ionize at environmental pH levels (that are generally 7 and lower) or not.

Acute toxicity to earthworms